Pharmaco-Metabolomics for Anticancer Drugs

Pharmaco – Therapeutics of Dasemani Drugs

The author scans in this paper the drug classification of Ayurvedic science grouped under two distinct heads of Botanical and therapeutic planes with modern equivalents. Also he throws some light on grouping of drugs done by Caraka the author of Caraka Samhita with special references to anti-inflammatory, Anti-haemorridal and Anti-asthmatic Dasemani drugs.

Assessment of the efficacy of anticancer drugs by amino acid metabolomics using fluorescence derivatization-HPLC.

Metabolomic studies conducted for evaluating cancer pathogenesis and progression by monitoring the amino acids metabolic balance hold great promise for assessing current and future anticancer treatments. We performed a comprehensive quantification of 21 amino acids concentrations in cultured human colorectal adenocarcinoma cells treated with the anticancer drugs 5-fluorouracil, irinotecan, and ...

Natural Based Anticancer Drugs and Their Worthiness

Metabolomics: a tool for anticancer lead-finding from natural products.

Natural products have been the source of many drugs used in modern therapeutics, and particularly in the case of anticancer drugs, more than 50 % originally came from natural products. Their importance as a source of leads for new drugs therefore cannot be underestimated. However, due to the painstaking way of conventional lead-finding, the attention towards natural products has been deviated i...

Chromatography of Anticancer Drugs

Chromatographic techniques have been developed and successfully applied for the analysis of a considerable of number of organic and inorganic compounds present at trace level in sometimes complicated accompanying matrices. The rapid development of new chromatographic instrumentation and separation strategies resulted in the increase of the number of chromatographic technologies with higher sepa...